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The illustration shows floating chromosomes with a Y-shaped chromosome in the foreground.
Closing the Gaps in the Human Genome: Why Y Was the Final Hurdle
For two decades, scientists struggled to fully sequence the Y chromosome. Finally, researchers have mapped its full length thanks to recent advances in sequencing technology.
Closing the Gaps in the Human Genome: Why Y Was the Final Hurdle
Closing the Gaps in the Human Genome: Why Y Was the Final Hurdle

For two decades, scientists struggled to fully sequence the Y chromosome. Finally, researchers have mapped its full length thanks to recent advances in sequencing technology.

For two decades, scientists struggled to fully sequence the Y chromosome. Finally, researchers have mapped its full length thanks to recent advances in sequencing technology.

News & Opinion

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A Novel Tool to Explore the Gut-brain Connection
Anna Napolitano, PhD | Aug 28, 2023 | 3 min read
Scientists used a vibrating capsule to assess people’s gut sensitivities and understand how the brain interprets these signals.  
A light gray mouse against an orange background listens to tiny headphones
Journey to the Center of the Ear
Niki Spahich, PhD | Aug 28, 2023 | 5 min read
An aqueduct connecting the brain to the ear may make gene therapy for hearing loss less invasive.
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Predicting the Next Level of CRISPR Control
Deanna MacNeil, PhD | Aug 28, 2023 | 3 min read
Scientists combine the power of genome-wide screens and machine learning to unlock the secrets of transcriptome engineering with Cas13.
landscape of frozen river
Worms Frozen for 46,000 Years are the Oldest Known Living Animals
Natalia Mesa, PhD | Aug 15, 2023 | 5 min read
Nematodes buried in Siberian permafrost may be able to stay in a state of suspended animation indefinitely, according to recent findings.
A close-up of the human eye, showing a colorful iris, black pupil, and transparent cornea.
Specialized T Cells Patrol Human Cornea
Rebecca Roberts, PhD | Aug 22, 2023 | 4 min read
A new imaging technique puts the immune system of the eye in perspective, challenging a long-held status quo. 
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Defending against Dravet
Aparna Nathan, PhD | Aug 21, 2023 | 3 min read
Gene therapy may be the first step toward curing a rare genetic epilepsy.
Blood vessel with flowing red blood cells and white immune cells.
New CRISPR Treatment Could Prevent HIV Reinfection after Viral DNA Excision
Jennifer Zieba, PhD | Aug 21, 2023 | 3 min read
Researchers design dual CRISPR treatments to remove HIV DNA and prevent reinfection in vitro.
A graph showing how scGPT groups cells, each represented as a dot, into cell types, shown as clusters of dots of the same color.
A New AI Tool Predicts Gene Expression in a Single Cell
Carissa Wong, PhD | Aug 21, 2023 | 4 min read
An artificial intelligence tool, scGPT, can identify cell types, predict the effects of disrupting genes, and pinpoint which genes interact with each other.
Six black-and-white MRI images of a brain at different cross-sections.
Is DIANA fMRI Data Real?
Ida Emilie Steinmark, PhD | Aug 17, 2023 | 4 min read
New preprints failed to reproduce the buzzy new neuroimaging technique DIANA fMRI, but its inventor remains steadfast.
A transverse section of stem wood from the researchers’ greenhouse-grown poplar tree.
CRISPR Trees Could Improve Paper Production
Alejandra Manjarrez, PhD | Aug 15, 2023 | 3 min read
Researchers edited several tree genes to improve suitability and sustainability in the pulp and paper industry.
A drawing of the sun on the sand, surrounded by items that people use to protect themselves from UV damage, including sunscreen, a hat, and sunglasses.
Taking Snapshots of DNA Damage in Skin Cancer
Deanna MacNeil, PhD | Aug 15, 2023 | 3 min read
Researchers turn to high resolution sequencing to explain recurrent melanoma mutations caused by UV exposure.
Caenorhabditis elegans, a free-living transparent nematode (roundworm), about 1 mm in length.
The Body, Not the Brain, Regulates Sleep
Rebecca Roberts, PhD | Aug 15, 2023 | 3 min read
Genetic screens have revealed three peripheral tissue genes that regulate sleep. What does this mean for sleep research?
Professor Alexandra Whiteley and graduate student Autumn Matthews look at an image of a western blot on their laboratory computer.
An Ancient Viral Protein May Play a Key Role in ALS
Aditi Subramaniam, PhD | Aug 15, 2023 | 4 min read
Researchers find that UBQLN2 gene dysfunction causes a virus-like protein to accumulate in cells, which changes gene expression and may contribute to disease progression in amyotrophic lateral sclerosis (ALS).
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Surreal illustration of the mind, represented by a person-shaped iceberg. A scuba diver illuminates the dark side of the iceberg underwater with a flashlight.
Toward Better Biomarkers for Schizophrenia
Deanna MacNeil, PhD | Aug 7, 2023 | 3 min read
Researchers scratch the surface of schizophrenia susceptibility by uncovering DNA methylation differences in neonatal blood samples.
Medical illustration of brain cancer with a microscopic magnification of malignant cells dividing in the tumor microenvironment.
Capturing the Brain Tumor Microenvironment with Tissue Engineering
Deanna MacNeil, PhD | Aug 4, 2023 | 3 min read
Researchers built a 3D glioblastoma model to study therapeutic resistance and improve drug screening systems.
Conceptual image of hair loss showing trees in the shape of a human head at various seasonal stages of shedding their leaves.
Islands of Knowledge: Hairy Skin Moles Make Their Mark
Iris Kulbatski, PhD | Aug 7, 2023 | 3 min read
Skin moles that sprout thick, long hairs produce signaling molecules that stimulate hair follicle stem cells to initiate new hair growth. This discovery may make baldness a thing of the past.
Dendritic Cell activate T cells, trigger immune responses, they are responsible of cells protection of the body.
Circadian Signaling Affects T Cell Responses to Vaccination
Nathan Ni, PhD | Aug 9, 2023 | 3 min read
Annie Curtis’s research team revealed how circadian rhythm-regulated mitochondrial metabolism drives dendritic cell antigen presentation activity.
Doctor in rubber gloves wiping injection site on arm of little girl before vaccination
Vaginal Delivery Promotes Early Childhood Vaccine Response
Jennifer Zieba, PhD | Aug 8, 2023 | 3 min read
Researchers showed that the delivery method affects the microbiome and plays a role in the infant vaccine immune response.
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